Journal of Pharmacobio-Dynamics
Online ISSN : 1881-1353
Print ISSN : 0386-846X
ELEVATION OF SERUM INDOLEACETIC ACID LEVELS IN RATS WITH EXPERIMENTAL LIVER FAILURE
JUN YAMADAYUMI SUGIMOTOKAZUYOSHI HORISAKA
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Keywords: D-galactosamine
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Volume 8 (1985) Issue 9 Pages 780-784

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Abstract

Changes in the serum levels of indoleacetic acid (IAA) of liver-injured rats induced with an injection of carbontetrachloride (CCl4) or D-galactosamine (GalN) were investigated. IAA showed a marked increase of 61.8% and 102.6% in CCl4 and GalN treated rats, respectively. The elevation of IAA was observed only in the early stages of hepatic failure.

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© The Pharmaceutical Society of Japan
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