Journal of Pharmacobio-Dynamics
Online ISSN : 1881-1353
Print ISSN : 0386-846X
ISSN-L : 0386-846X
REDUCTION OF ACETOHEXAMIDE BY RABBIT HEART CYTOSOL
YORISHIGE IMAMURAYUICHIRO KOJIMAMASAKI OTAGIRI
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Keywords: ketone reductase
JOURNAL FREE ACCESS

1986 Volume 9 Issue 1 Pages 110-111

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Abstract
The acetohexamide reducing activity of cytosol of rabbit heart was compared with that of rabbit liver or kidney. The heart exhibited an approximately 2-fold higher activity than either the liver or kidney. Both aldehyde and ketone reductases may contribute to the reduction of acetohexamide by cytosol of rabbit heart. It is noteworthy that the heart is an important organ reducing acetohexamide.
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© The Pharmaceutical Society of Japan
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