Biological Sciences in Space
Online ISSN : 1349-967X
Print ISSN : 0914-9201
ISSN-L : 0914-9201
Protein Homeostasis-Small Heat Shock Proteins and Cytoskeleton
Eri Fujita
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2008 Volume 22 Issue 4 Pages 148-157

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Abstract
Cells can moderately stabilize their structure and keep their dynamic property in response to stress signals from outside the cells. The stress response signal system - the expression of stress proteins is necessary to maintain cell function not only in stress but also in non-stress condition. Cytoskeletal proteins comprised of cell structure and cell movement are not fixed structure but dynamic skeletal scaffold. Stress protein, αB-crystallin, might stabilize dynamic property of cytoskeleton. αB-crystallin is constitutively expressed in anti-gravity muscle, so that its function relates with gravity. Stress protein as sustainable basis of cytoskeleton dynamics plays role in remodeling of cytoskeleton, response to exercise.
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© 2008 by Japanese Society for Biological Sciences in Space
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