Abstract
Cells can moderately stabilize their structure and keep their dynamic property in response to stress signals from outside the cells. The stress response signal system - the expression of stress proteins is necessary to maintain cell function not only in stress but also in non-stress condition. Cytoskeletal proteins comprised of cell structure and cell movement are not fixed structure but dynamic skeletal scaffold. Stress protein, αB-crystallin, might stabilize dynamic property of cytoskeleton. αB-crystallin is constitutively expressed in anti-gravity muscle, so that its function relates with gravity. Stress protein as sustainable basis of cytoskeleton dynamics plays role in remodeling of cytoskeleton, response to exercise.