Abstract
As long-term human space flight is now required for cosmic exploration, the influence of space radiation and microgravity on the human body is an issue of high priority. We plan to launch frozen mouse embryonic stem (ES) cells into space, to expose them to space radiation. After returning to the ground, we will microinject the ES cells into fertilized eggs to produce mice, and evaluate the influence of space radiation on their development and on their descendents.
