BioScience Trends
Online ISSN : 1881-7823
Print ISSN : 1881-7815
ISSN-L : 1881-7815

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From light to insight: Functional near-infrared spectroscopy for unravelling cognitive impairment during task performance
Na LiuLingling YangXiuqing YaoYaxi Luo
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ジャーナル フリー 早期公開

論文ID: 2024.01362

この記事には本公開記事があります。
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Cognitive impairment refers to the impairment of higher brain functions such as perception, thinking or memory that affects the individual's ability to perform daily or social activities. Studies have found that changes in neuronal activity during tasks in patients with cognitive impairment are closely related to changes in cerebral cortical hemodynamics. Functional near-infrared spectroscopy is an indirect method to measure neural activity based on changes in blood oxygen concentration in the cerebral cortex. Due to its strong anti-motion interference, high compatibility, and almost no restriction on participants and environment, it has shown great potential in the research field of cognitive impairment. Recognizing these benefits, this comprehensive review systematically elucidates the rationale, historical development, advantages and disadvantages of functional near-infrared spectroscopy, and also discusses the applications of combining functional near-infrared spectroscopy with other detection techniques. Additionally, this review summarized how functional near-infrared spectroscopy can be applied to cognitive impairment caused by different diseases, ultimately aiding the study of neural mechanisms of cognitive activities, which is crucial for the diagnosis, differentiation and treatment of cognitive impairment.

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