THE BULLETIN OF TOKYO MEDICAL AND DENTAL UNIVERSITY
Online ISSN : 2435-0761
Print ISSN : 0040-8921
IMMUNOLOGICAL INVESTIGATION ON TRANSPLANTABLE RABBIT TUMOR
Hiroshi IWASAKenichiro IMAMURAToshinori ISHIIHiromi SEKIZUKAHiromitsu KASHIWADEHayato HASEKURA
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JOURNAL OPEN ACCESS

1972 Volume 19 Issue 2 Pages 191-210

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Abstract
The immunological variables of cancer-bearing individuals are quite important in the diagnosis, decision of treatment and judgement of prognosis, but sufficient indicators are not determined as yet today. Variations of the immunological activities were tested using the Vx2 tumor-bearing rabbits. Titrations of the humoral agglutinin did not show significant results, but the cell-mediated immune activity suggested strong effects, thus leading us to the treatment of Vx2 tumor with sensitized lymphocytes, which proved to destroy and cure the tumor completely, if the tumor is in the incipient stage. These results are expected to be confirmed and applied to the human tumor.
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© 1972 Tokyo Medical and Dental University (TMDU)
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