THE BULLETIN OF TOKYO MEDICAL AND DENTAL UNIVERSITY
Online ISSN : 2435-0761
Print ISSN : 0040-8921
Volume 19, Issue 2
Displaying 1-4 of 4 articles from this issue
  • Modaser SHAH, Wataru MORI
    1972 Volume 19 Issue 2 Pages 165-177
    Published: 1972
    Released on J-STAGE: November 13, 2021
    JOURNAL OPEN ACCESS
    The following tentative conclusions were drawn from a study of 123 histologically confirmed cases of liver diseases in Peshawar, Pakistan, and from a comparison of these with biopsy and autopsy cases seen at the Department of Pathology, Tokyo Medical and Dental University: 1. Cirrhosis as it exists in the North West Frontier Province of Pakistan is morphologically the same disease as that found in Japan, and our classification seems to be applicable to both. 2. The main varieties of cirrhosis found are similar, with predominance of types A (“postnecrotic”) and B (“posthepatitic”), in both Peshawar and Tokyo. 3. It is possible that hepatoma has a high frequency in Peshawar, and it may be expected to rise further as the age composition of the population changes. The same conclusion seems to apply to other, areas of Pakistan and Afghanistan. 4. Cholangioma appears to be relatively rare, and is not associated with parasitic infestation, as is the case in China and Thailand. 5. Infective hepatitis exists in Peshawar, and deserves consideration as a possible factor in the causation of cirrhosis and hepatoma. 6. Fatty liver is infrequent, a phenomenon probably due to teetotalism.
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  • Yoshio MITOMO, Wataru MORI
    1972 Volume 19 Issue 2 Pages 179-189
    Published: 1972
    Released on J-STAGE: November 13, 2021
    JOURNAL OPEN ACCESS
    It is very difficult to utilize a specific electron microscopic method for all cases in the routine examination of surgical and autopsy materials. The utilization of paraffin embedded material for electron microscopy has already been described by Zeitoun and Lehy but finer cytological details are difficult to distinguish by their method. The present method is possible to preserve the ultrastructure well by a more simple procedures, in which the paraffin or celloidin-paraffin embedded tissue is mounted on an epoxy resin slide instead of glass slide, embedded in epoxy resin through deparaffinization, dehydration, staining, post-fixation with osmium tetroxide, and sampling of the area to be chosen for electron microscopy is made under a light microscope. The precise selected region can be easily ultrathin sectioned and electron micrographs taken. Through this procedure, the virus particles with a nucleoid core are observed in the cytomegalic inclusion bodies of salivary gland and the tumor cells of giant cell tumor of tendon sheath can be divided into two main types; one richly endowed with rough endoplasmic reticulum and the other containing many mitochondria. This method is useful for obtaining ultrastructural informations for the examination of difficult diagnostic cases in the surgical and autopsy pathology.
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  • Hiroshi IWASA, Kenichiro IMAMURA, Toshinori ISHII, Hiromi SEKIZUKA, Hi ...
    1972 Volume 19 Issue 2 Pages 191-210
    Published: 1972
    Released on J-STAGE: November 13, 2021
    JOURNAL OPEN ACCESS
    The immunological variables of cancer-bearing individuals are quite important in the diagnosis, decision of treatment and judgement of prognosis, but sufficient indicators are not determined as yet today. Variations of the immunological activities were tested using the Vx2 tumor-bearing rabbits. Titrations of the humoral agglutinin did not show significant results, but the cell-mediated immune activity suggested strong effects, thus leading us to the treatment of Vx2 tumor with sensitized lymphocytes, which proved to destroy and cure the tumor completely, if the tumor is in the incipient stage. These results are expected to be confirmed and applied to the human tumor.
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  • Makoto MATSUMOTO, Tadamasa GOTO, Teruo TATEISHI
    1972 Volume 19 Issue 2 Pages 211-235
    Published: 1972
    Released on J-STAGE: November 13, 2021
    JOURNAL OPEN ACCESS
    This investigation was carried out for the purpose of analyzing the functional behavior of the removable partial denture with unilateral extension saddle, particularly to relationship between the denture design and the residual ridge form. For this purpose, four different types of residual ridges in clinically simulated mandibular models and three different types of testing dentures for each model were made. The previously reported special devices for measuring the tooth mobility, force applicator, and a micro-dial-gauge, and also their recording system were used. Using these systems, the amount of the lateral excursion of abutment tooth for the direct and indirect retainers was measured for three types of dentures on each model while a known force was applied on the occlusal table of the testing dentures. A personal computor was used for the statistical analysis of these data and the conclusions were as follows: i) The transmitting force to the abutment teeth was highly affected by the condition of residual ridge form and by denture designs while known vertical and lateral forces were applied on the occlusal table of the distal area. ii) On the residual ridge with excess bucco-lingual bone loss, the so called rocking axis of denture was located on the crest of the residual ridge, but location of the rocking axis was completely irregular on the residual ridge with excess bone loss in the second and third molar area. iii) The twisting point or shifting axis on the occlusal table appeared as a spot in A-type denture and its location moved according to residual ridge conditions. This point or area on the occlusal table was moved greatly by the factor of the residual ridge when the B- type denture was applied. ⅳ) The amount of vertical excursion of the extension saddle-type denture against vertical loading was highly affected by denture design rather than by the residual ridge. v) The location of the torque fulcrum of the free end saddle denture can also be changed by the denture design. vi) The optimal occlusal pattern of the removable partial denture of the extension saddle type change with denture design and residual ridge.
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