MIXED LYMPHOCYTE TUMOR CELL CULTURE TEST IN GASTRIC CANCER PATIENTS

Hiroshi IWASA; Hiromi SEKIZUKA; Kunihide YOSHINO; Hideto SHINOHARA; Hideto TANIGUCHI; Kazuo MIMURA; Akira KASHIMURA; Tadashige MURAKAMI

doi:10.11480/btmd.210204

Hiroshi IWASA, Hiromi SEKIZUKA, Kunihide YOSHINO, Hideto SHINOHARA, Hideto TANIGUCHI, Kazuo MIMURA, Akira KASHIMURA, Tadashige MURAKAMI

Author information

Hiroshi IWASA
1st Department of Surgery, School of Medicine, Tokyo Medical and Dental University [Japan]
Hiromi SEKIZUKA
1st Department of Surgery, School of Medicine, Tokyo Medical and Dental University [Japan]
Kunihide YOSHINO
1st Department of Surgery, School of Medicine, Tokyo Medical and Dental University [Japan]
Hideto SHINOHARA
1st Department of Surgery, School of Medicine, Tokyo Medical and Dental University [Japan]
Hideto TANIGUCHI
1st Department of Surgery, School of Medicine, Tokyo Medical and Dental University [Japan]
Kazuo MIMURA
1st Department of Surgery, School of Medicine, Tokyo Medical and Dental University [Japan]
Akira KASHIMURA
1st Department of Surgery, School of Medicine, Tokyo Medical and Dental University [Japan]
Tadashige MURAKAMI
1st Department of Surgery, School of Medicine, Tokyo Medical and Dental University [Japan]

JOURNAL OPEN ACCESS

1974 Volume 21 Issue 2 Pages 241-250

DOI https://doi.org/10.11480/btmd.210204

Details

Abstract

In twenty-eight gastric cancer cases the MLTC was performed. X-ray-irradiated tumor cells or MMC-treated tumor cells were cultured with autologous lymphocytes and with 3H-thymidine added. In the autoradiography group 2 out of 8 cases and in the liquid scintillation counter group 3 out of 20 cases the uptake of 3H-thymidine by the cells increased more than in the controls. In observing the results of the 1st and 2nd culture in the autoradiography group, and effect of lymphocyte reactivity following the surgical removal of the tumors was observed.

Corresponding author

Register with J-STAGE for free!