STUDIES ON THE IRON CONTENT OF RAT LIVER DURING p-DIMETHYLAMINOAZOBENZENE CARCINOGENESIS
1952 Volume 43 Issue 4 Pages 437-441
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1952 Volume 43 Issue 4 Pages 437-441
The iron content of the liver of rats during the butter yellow (p-dimethylaminoazobenzene) carcinogenesis was determined. It was demonstrated that there was an initial elevation, which, however, decreased gradually proportional to hepatic changes. The peak of the iron content was at the early stage of the liver changes and the content was more than twice the normal. In the liver cancer, the iron content showed the lowest value which was only 58 per cent of normal.
At the end of this paper it is pleasure to express our appreciation to Dr. S. Kishi for his kind advice on the experiment.
