SOME ASPECTS OF THE CHROMOSOME CONSTITUTION OF HYDATIDIFORM MOLES AND NORMAL CHORIONIC VILLI
1962 年 53 巻 2 号 p. 101-106_1
詳細
1962 年 53 巻 2 号 p. 101-106_1
Six cases of hydatidiform moles and three cases of normal chorionic villi were subjected to cytological study, particularly on the number and morphology of the chromosomes.
In all cases from the two sources considered, the modal number of chromosomes was found to be 46. The chromosomes were of a normal pattern in both number and morphology with either the female or male karyotypes. A considerable number of polyploid cells occurred in cell populations derived from hydatidiform moles, while in those from normal chorionic villi incidence of polyploidy was very low. Further, abnormal mitotic cells showing endoreduplication, clumping and scattering of the chromosomes were frequent in some mole specimens.
