抄録
Production of immunoglobulins and of herpes-type EB virus in newly established four cell lines, RS-2, RS-3, MC-8, and MC-12, derived from human neoplastic lymph nodes was investigated by means of immunofluorescence. Cells producing at least one of three classes of immunoglobulins, IgG, IgM, and IgA, were demonstrated in all of the four cell lines tested. This finding suggests that lymphoreticular cells are contained in the cell population of these cultures. EB virus antigen was detected in 2-10% of the cells of all the cell lines. Antibody against EB virus as revealed by indirect immunofluorescence method was demonstrated in all of the test sera obtained from the donors of these cultures.
