GLUCOSE-INDUCED pH CHANGES IN EHRLICH ASCITES TUMOR CELLS

Abstract

Ehrlich ascites tumor cells were incubated with glucose or fructose in saline for 1 hour at 37° without shaking. The final pH of the local extracellular fluid was calculated to be between 4.21 and 4.50. Nonglycolytic sugars did not lower pH. Decreased pH is discussed as a factor in glucose-induced loss of tumor cell transplantability.