SELECTIVE DISTRIBUTION OF THE RADIOACTIVITY IN NERVE TISSUES OF THE MOUSE AFTER INTRAVENOUS ADMINISTRATION OF ¹⁴C-LABELED N-METHYL-N'-NITRO-N-NITROSOGUANIDINE

抄録

Macroautoradiographic studies on the distribution of ¹⁴C-labeled N-methyl-N'-nitro-N-nitrosoguanidine (MNNG-¹⁴C) in mice revealed that radioactivity derived from MNNG distributed selectively in nerve tissues 1hr after intravenous administration but not 5hr later. Such a phenomenon cannot be seen after oral administration.