RECOVERY IN BURKITT LYMPHOMA CELLS AFTER X-RAY IRRADIATION

Abstract

The radiation response of cultured Burkitt lymphoma cell, known as a particular cell line of high radiosensitivity, was studied by the colony formation method. The values of n, D_q, and D₀ derived from the survival curve after a single dose X-irradiation resulted in small values as 1.1, 10rad, and 125rad. The maximum recovery of about 5% was observed 3hr after the irradiation by a split-dose experiment. In the survival curve derived from a split-dose irradiation, n and D_q increased while D₀ remained unchanged. The reason for these increases in n and D_q may be attributed to the nonhomogeneous or mixed population response.