2018 Volume 30 Issue 1 Pages 17-22
We introduce our basic and clinical researches to improve the prognosis of the patients suffering from acute ischemic stroke and discuss their future. 1) A nationwide project to promote endovascular therapy for acute stroke (RESCUE-Japan Project): Although clinical evidence was established, mechanical thrombectomy is not widespread in our country. We started promotion of this treatment over the country based on our nationwide surveillance. 2) Development of a new computer application to predict stroke subtypes at prehospital: In acute cerebral large vessel occlusion, the affected vessels should be recanalized as soon as possible for better patient’s outcome. We developed a new computer application to predict stroke subtypes, and would be useful for patient transferring system. 3) A clinical trial regarding lipid lowering therapy for acute stroke and carotid/intracranial artery stenosis: Based on our previous clinical studies, we will start a new study to elucidate the efficacy and safety of PCSK-9 inhibitor. 4) Basic and clinical studies of cell therapy for acute ischemic stroke: We will start clinical trial of cell therapies using bone-marrow mononuclear cells, and ischemia-induced multipotent stem cells (iSCs) to improve clinical outcome of acute stroke patients.
