Risk estimation for growth and rupture of cerebral aneurysms

Abstract

Inflammatory process has been reported to play a significant role in the pathogenesis of cerebral aneurysmal development, growth and rupture, and new possible treatment modalities has been investigated. Clinical cohort studies have produced a new scoring system to estimate risk of aneurysmal rupture, and recent development in vascular wall imaging for cerebral aneurysms also has a possibility to evaluate aneurysmal rupture risk. Preventive pharmacological intervention with anti-inflammatory agents might inhibit aneurysmal growth and rupture, and further precise risk estimation for cerebral aneurysmal rupture is warranted.