Abstract
The structure of the auto-staining apparatus for teratological specimens newly developed by us was explained, and the most appropriate procedure of skeletal staining with alizarin red S for teratological investigations with this apparatus was described. This auto-staining apparatus enables us to stain the skeleton of about 200 specimens of mouse or rat fetuses, about 50 specimens of the reared young of rats, or about 70 specimens of the reared young of mice, at the same time in a day, and thus the labor and time required for the skeletal staining in the course of teratological investigations can be saved.