official journal of Congeital Anomalies Research Association of Japan
Online ISSN : 2433-1503
Print ISSN : 0037-2285
Effect of Urethan on Human Limb Development in Vitro
Yoshiko YASUDA
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1978 Volume 18 Issue 2 Pages 63-68

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Abstract
The effect urethan on humen limd development in vino was seen in limbs from embroys Streeter's (H.) XII to XVI cultured with urethan (50 μ/ml) for four days. In limbs from H. XII to XVI embroys, the mitotic inter ference in significant differences in the appearance of bone blastemata and differential state of cartilage were detected between the experimental and control explants. Thus, the present xeperiment showed that urethan affected human limb morphogenesis and the sensitive period to urethan was XII to XIV.
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© 1978 The Japanese Teratology Society
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