DRUG RESISTANCE OF GRAM NEGATIVE BACTERIA OF CLINICAL SIGNIFICANCE. I

Abstract

Drug resistance and biological properties of 261 strains of gram negative bacteria were investigated. These strains were isolated in 1965 from patients at 14 hospitals, with the cooperation of 16 participating laboratories. The strains included Escherichia coli (44. 1%), Pseudomonas aeruginosa (25. 3%), Proteus (11. 5%), Klebsiella (8. 8%) and others (10. 3%). It was found that almost all of these strains were multiply resistant. The strains harboring transmissible drug-resistance-factor “R” included E. coli, Proteus and Klebsiella, which belong to the Enterobacteriaceae. This report also oonfirms similar findings in suggesting that R factors are widely distributed in gram negative bacteria of clinical significance.