Abstract
Primary or secondary disturbances to various physical functions, especially those related to the reticuloendothelial system in cancer patients may be induced with relation to the malignant growth. The results of a number of investigations suggest that reduction of activities of the general defense mechanisms due to above factor may be favorable to malignant growth.
Therefore, the stimulation of the activities of the defense mechanism could be inhibited by the tumor growth.
With this point of view, the author and his collaborators have studied on the value of activation of the physical functions of a cancer bearing host and its combination with cancer chemotherapy; that is, the effect of administration of stimulating agents to the reticuloendothelial system (including liver tonics, stroma-affecting agents), of massive dose of protein (amino acid preparation), of various bacterial vaccine, and of hormone of the opposite sex.
Thus, it will be summarized that one of th e most promising approaches to cancer therapy at the present time is a combination of anti-cancer chemotherapeutic agents together with agents that stimulate the activities of the defense mechanism of the host.
