1968 年 16 巻 1 号 p. 82-86
In order to certain the clinical effect and prognosis of the concomitant administration of, a chemotherapeutic agent and an analgesic, we studied the clinical results of the use of Sulfisomezole and a nonpyrine analgesic S-207 simultaneously administered in ombination. Female patients with simple acute cystitis were picked up at random but in the order or their registering themselves at the receptionist desk of our Department, for the studies of the effect of treatment by the double blind technique. The cases so studied numbered 23. A control placebo group comprised 22 cases.
In terms of the number of days required for the symptoms and complaint s to decrease and clear, theS-200 group showed much better results in such?stibjectiveSyMptoms aspain on micturition, pal lakisuria, etc. No difference was noted between the two groups, on the other hand, in the number of days for the urine to become negative. Therefore, under the consideration of the sensitivity of the isolated organisms and also the effect on antibacterial activity as deterirtined by variations in the leukocyte count in the urinary sediments, the use of Sulfisomezole and S-207 concomitantly has been found to be an effective and adequate therapy.