STUDIES ON THE SYNERGISTIC ACTION OF AMINOBENZYL-PENICILLIN. AND METHYLCHLOROPHENYLISOXAZOLYL-PENICILLIN. I

Antibacterial Activity in vitro

Abstract

1) When AB-PC and MCI-PC were combined in vitro, the antibacterial spectrum tended to be extended in comparison with each one of the antibiotics.
2) The antibacterial activities in vitro ag ainst various bacteria were not remarkably influenced by the rates of combination (2: 1, 1: 1, 1: 2) of both antibiotics.
3) The synergism of AB-PC and MCI-PC in vitro was demonstrated in various bacteria, but the degrees of synergistic activities varied among the bacteria and strains used.