1973 年 21 巻 2 号 p. 128-136
Bacteriostatic effect has been variously affected against anaerobesly to trimethoprim (TMP) and sulfamethoxazole (SMX) combination drug by inoculum size.
We think that sensitive anaerobes to TMP or SMX have the enhanced activity by the combination of TMP and SMX, while high resistant anaerobes have not.