1973 年 21 巻 2 号 p. 464-466
SMX-TMP combination was administered orally daily 4 tablets for 7 days to 30 female patients with acute cystitis. The therapeutic results were remarkable in 19 patients, fair in 11, with the effectiveness rate of 100 per cent.
FIC index of SMX-TMP combination against Escherichia coli (19 strains) was below. 0.3 in 10 strains, between 0.41 and 0.5 in 8 strains and about 0.6 in 1 strain.
Side effects were found in 4 patients, being in 1 case stomachache, which disappeared after administration was stopped.