Cephradine (CED) の尿路感染症に対する臨床治験
1975 年 23 巻 1 号 p. 361-368
詳細
1975 年 23 巻 1 号 p. 361-368
Cephradine (CED) was applied clinically in 20 cases of tract infection, and the results were obtained as follows.
1) Among 14-ases of acute urinary tract infection, the results obtained were excellent in 13 cases and fair in 1 case, effective ratio being 92.8%.
Among 6 cases of chronic urinary tract infection, the results were excellent : in 3 cases and poor in 3 cases, effective ratio being 50%.
On the whole, 20 cases resulted in excellent in 16 cases, fair in 1 case and poor in 3 cases, showing 80% as effective ratio.
2) MIC of cephradine and cephalexin was measured against various bacteria, and the antibacterial.activity of cephalexin was 1-2 grades stronger than that of cephradine against. E. coli and Klebsiella.
This was noticed similarly against Staphylococcus, Pseudomonas and Gram-positive diplococcus.
3) As a side effect with the drug, GOT and GPT values rose in one case.
