CLINICAL STUDIES ON AMIKACIN (BB-K8)

Abstract

1) Amikacin (BB-K8) was administered to 21 patients of various infections, and showed the excellent or good response in 14 cases.
2) In the patients with normal renal function, amikacin should be used above 400 mg daily to obtain a good clinical response.
3) No remarkable side effect was observed in kidney, liver, and bone marrow functions, but in auditory function, 3 patients seemed to be slightly damaged among the 5 investigated patients. Two of them were old, and 1 was uremic.