ゲンタマイシン耐性菌の研究

抄録

1) Two hundreds and nineteen strains, with minimal inhibitory concentration of 12.5μg/ml or higher for gentamicin, were isolated from 6 hospitals in Tokyo and Chiba.They were Pseudomonas aeruginosa (73 strains), Providence (56 strains), Proteus sp. (36 strains), Klebsiella-Enterobacter-Serratia (33 strains), E. coli (9 strains), Alcaligenes (5 strains), Acinetobacter (4 strains), Citrobacter (3 strains) and Pseudomonas cepacia.
2) Incidence and species of bacteria resistant to gentamicin varied in each hospital. The major sources of these bacteria were urine and pus.
3) These bacteria are commonly resistant to kanamycin, dibekacin and tobramycin. Of these Pseudomonas aeruginosa, Proteus sp. and Providence, 3strains were inhibited by kanamycin and dibekacin and 12 strains by tobramycin at the concentration of 6.3μg/ml.
4) Forty-seven strains of 73 Pseudomonas aeruginosa, 33 strains of 56 Providence and 22 strains of 33 Proteus sp. were susceptible to 6.3μg/ml of amikacin.