耳鼻咽喉科領域におけるPipemidic acidの臨床使用経験

抄録

Pipemidic acid was administered to 14 cases of chronic suppurative otitis media at a daily dose of 1.5 or 2 g for 6 to 10 days. Clinical results were effective in 7 cases, slightly effective in 3 cases and ineffective in 4 cases. The efficacy rate was 50 %. It was interesting that some cases due to gram-negative bacilli, especially 3 cases due to Pseudomonas aeruginosa, were favorably treated with this drug because such cases were usually difficult to be cured. No side effects were observed in all cases treated.