CHEMOTHERAPY
Online ISSN : 1884-5894
Print ISSN : 0009-3165
ISSN-L : 0009-3165
COMBINED ACTION OF T-1220 AND GENTAMICIN AGAINST PSEUDOMONAS AERUGINOSA AND SERRATIA MARCESCENS
ISAMU SAIKAWA, TAKASHI YASUDA, MASARU TAI, MASAHIRO TAKAHATA, HISATSUGU TSUDA, MICHIKO NAKAGAWA
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1977 Volume 25 Issue 5 Pages 797-800

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Abstract
The combination of T-1220 and Gentamicin enhanced the antibacterial activity in vitro against clinically isolated strains of Pseudomonas aeruginosa and Serratia marcescens. Bactericidal activity against P. aeruginosa S-68 was enhanced by combining the two antibiotics.
Synergistic activity of the two antibiotics was also observed in protective effect against experimental infection in mice by P. aeruginosa S-68.
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© Japanese Society of Chemotherapy
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