CLINICAL RESULTS OF ADMINISTRATION WITH FOSFOMYCIN CAPSULE IN URINARY TRACT INFECTIONS
1977 Volume 25 Issue 8 Pages 2338-2347
Details
1977 Volume 25 Issue 8 Pages 2338-2347
Fosfomycin was administered orally in 42 cases with acute or chronic urinary tract infections.
1. The clincal results were excellent or good in all of 15 cases with acute simple urinary tract infections.
2. Out of 27 cases with urinary tract infections complicated or after surgery, very satisfactory results were obtained, that is, excellent in 14 cases, good in 7 cases, and poor in 6 cases. As to the excellent efficacy rate, the cases after surgery were especially superior to the complicated cases. It was remarkable that the excellent effect was observed even in the infections with Proteus, Klebsiella, Pseudomonas, or Serratia. No correlation was observed between MIC of Fosfomycin R against pathogens and bacteriological responses in complicated cases.
3. One patient complained of diarrhea, and no severe side effects were encountered.
4. Nowadays, the organisms resistant to antibiotics in common use are detected increasingly in chronic urinary tract infections. Fosfomycin-Ca may be thus expected in the treatment of these infections.
