1) The peak of serum and biliary level of ticarcillin following 3.0 g drip infusion were 166.0 and 100.0μg /ml respectively and the urinary excretion rate was 46.7% during 6 hours.
2) Ticarcillin was applied to 9 infections and 4 cases for the purpose of protection of post operative infections in the surgical field. Some of cases were combined therapy with GM, DKB and CLDM. The effective rate was 84.6% (11/13).
3) The daily dose was 6.0 g in 12 cases and 9.0-12.0 g in one case. The maximum total dose and duration were 186.0 g and 31 days respectively. No side effects were observed except a slight liver dysfunction after administration of ticarcillin was noticed in 1 case.
