The therapeutic efficacy of ticarcillin has been evaluated in 28 cases (33 strains) with complicated chronic urinary tract infection.
Ticarcillin was administrated by intramuscular injection for 2 to 10 days at a daily dose of 2 to 4 g.
Some effects were obtained in 21 cases, of which 11 cases showed remarkable effect.
Organisms isolated from patients were first Pseudomonas aeruginosa (15 strains), followed by 4 Citrobacter, 4 Klebsiella, 3 Proteus mirabilis, 2 E. coli and 4 other groups.
In spite of high MIC against Pseudomonas, clinical effect of ticarcillin was especially good : Some effect was observed in 14 strains among 15 strains, and remarkable effect in 6 cases of them.
As the side effect, one patient had severe pain at injected site and one had exanthema respectively after intramuscular administration of ticarcillin.
