CHEMOTHERAPY
Online ISSN : 1884-5894
Print ISSN : 0009-3165
ISSN-L : 0009-3165
MICROORGANISM DETECTED IN URINARY TRACT OF THE PATIENTS WITH SPINAL CORD INJURY AND THE ALTERATION OF THEIR POPULATION BY CHEMOTHERAPY-In Relation to Nosocomial Infection-
TAKEHIRO TSUJIMOTOHIROSHI YAMAKUNIO NAKAARAI
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1978 Volume 26 Issue 4 Pages 454-458

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Abstract

The alteration of population of infected organism cultivated from urine specimens in spinal cord injury patients was observed in relation to chemotherapy in each month from 1974 to 1975. Studies on nosocomial infection were also carried out using Pseudomonas aeruginosa as a target orgainsm. The following results were obtained.
Genus Proteus was detected most frequently, especialy Pr. rettgeri from 30 to 63% (average 50%) and secondary Ps. aeruginosa from 22 to 63% (average 44%). Both organisms were gradually reduced by vesical retention and washing due to polymyxin B solution, and other Proteus group and others increased subsequently.Serratia marcescens and Pr. morganii newly appeared and gradually increased in its populations. It is again recognized that chemotherapy replaced organisms to others.
Serological typing.Pseudomonas aeruginosa showed that type F was observed 68% in urine specimens from spinal cord injury patients who were admitted in the ward. In contrast, various types of Ps. aeruginosa were detected under 20% from the patients admitted in other wards. Our study indicated that nosocomial infection did not spread from the ward of spinal cord injury patients to other wards, but frequently occurred between the spinal cord injury patients within the ward.

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© Japanese Society of Chemotherapy
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