1980 Volume 28 Issue Supplement6 Pages 419-424
Clinical study was made on cefoperazone (CPZ, T-1551), a new cephalosporin derivative, and the following results were obtained.
1) CPZ was found effective in 60% of 14 patients with intractable respiratory tract infections to whom other drugs had not responded well.
2) CPZ was found markedly effective in all of 5 patients with diffuse panbronchiolitis and pulmonary emphysema caused by H. influenzae. CPZ was slightly effective in 2 of 7 patients with diffuse panbronchiolitis caused by P. aeruginosa and gram-negative bacillus.
3) CPZ caused fever and diarrhea in one patient and eosinophilia in one patient, but these symptoms were reversible after cessation of drug.
