1984 Volume 32 Issue Supplement2 Pages 272-280
1. MICs of TA-058 against 25 strains clinically isolated each of S. aureus, E. coli, K. Pneurnoniae, E. cloacae, P. mirabilis, and P. vulgalis were compared with those of AMPC and PIPC. Antibacterial activity of TA-058 was about similar to those of AMPC and inferior to those of PIPC.
2. Clinical effects of TA-058 in 4 cases of respiratory tract infection were evaluated as follows: excellent in 1, good in 1, fair in 1, and poor in 1 case.
Though we had only a few cases, it seemed that the clinical effects depended on a dosage of TA-058 from the above results.
3. Neither clinical side effects nor abnormal clinical laboratory findings were observed.