1984 Volume 32 Issue Supplement2 Pages 329-333
TA-058 was administered to 17 patients with respiratory tract infection. The clinical effectiveness was excellent in 4 patients, good in 9, fair in 3 and poor in 1. The clinical effective rate was 76.5%.
As side effects, one case showed a decrease in leucocyte counts from 3, 100/mm3 to 1, 400/mm3 four days' administration of TA-058, one case showed eosinophilia and one case showed slight elevations of GOT and GPT in serum.
The causative organisms were able to isolate in 14 cases: H. influenzae; 7 cases, S. pneumoniae; cases, H influenzae and S. Pneumoniae; 5 cases.
These organisms didn't yield after administration of TA-058 except one case isolated β-lactamase produced H. influenzae.