1984 Volume 32 Issue Supplement9 Pages 246-250
AC-1370 is a new cephalosporin antibiotics against a broad spectrum of gram-positive and gram-negative microorganisms especially Pseudomonas sp.
AC-1370 was used in the treatment of 10 cases of respiratory infectious diseases, 5 cases of pneumonia, 3 cases of chronic bronchitis, one case of diffuse panbronchiolitis and one case of acute bronchitis, AC-1370 was administered intravenously at a dose of 1.0×2.0g twice daily for 4 to 21 days and results obtained were excellent in one case, good in 4 cases, fair in 2 cases, poor in 2 cases and not determined in one case.
Adverse reaction such as drug eruption, fever, nausea, diarrhea and vascular pain were not observed. Abnormal laboratory findings were not observed.
From the above clinical studies, AC-1370 would be a clinically useful antibiotics against the respiratory infectious disease.
