CLINICAL STUDY ON CEFPIROME

Abstract

Cefpirome (CPR) was administered by intravenous drip infusion at 1 g b.i.d. to six patients with respiratory tract infections for 6.5-21 days. The results were good in four and poor in one of five cases of bacterial pneumonia and fair in one case of secondary infection of old pulmonary tuberculosis.
One strain each of the causative organisms Haemophilus influenzae and Streptococcus pneumoniae was eliminated by administration of CPR.
Apart from one case of elevated GOT, GPT, and LDH accompanied by fever, no adverse reactions or abnormal laboratory findings were noted following administration of CPR.