Clinical study of biapenem

Abstract

We studied the clinical efficacy and safety of biapenem (BIPM), a new carbapenem antibiotic, in pulmonary suppuration and infectious endocarditis. The clinical response was excellent in these cases. The causative organisms, Prevotella intermedia, Bactroides sp. and Peptostreptococcus sp. were isolated in pulumonary suppuration and were eradicated.
No side effect were observed, but the laboratory findings revealed GOT, GPT, ALP and LAP in pulmonary suppuration.