1994 Volume 42 Issue Supplement4 Pages 766-768
Biapenem (BIPM) was administered by intravenous drip infusion at 300mg b. i. d. to nine patients with respiratory tract infections for 7 to 10 days. The clinical responses were good in seven and poor in one of the two cases of bronchopneumonia and poor in one case of bronchitis. Of ten strains (4 species) isolated from seven patient before treatment, eight were eradicated after treatment, but two strains of P. aeruginosa persisted.
As abnormal laboratory findings, elevation of LDH and decrease of platelet and s-K eosinophilia were observed in one patient each.
The above results suggest that BIPM is a valuable and safe agent for treating respiratory tract infection.
