Abstract
We performed clinical and laboratory studies on biapenem (BIPM), in surgical infections. Ten patients received BIPM, the diagnoses was peritonitis 3, panperitonitis due to perforation of the gastric ulcer 1, pelvic peritonitis 1, suppurative cholangitis 1, cholecystitis 2, suppurative mastitis 1 and pyothorax 1.
The clinical efficacy of BIPM was excellent in 6 cases and good in 4 cases of the 10 cases, the overall efficacy rate being 100%.
Bacteriological efficacy was investigated in 5 cases: 4 were eradicated and 1 was decreased.
No side effects were observed, but the abnormal laboratory finding of slight elevations of GOT, GPT and ALP was noted in only 1 case.
