Clinical study of biapenem in the abdominal surgical field

Abstract

Biapenem (BIPM) was administered to 10 patients with abdominal surgery.
Clinical response was excellent in 9 cases and good in 1 case, and the overall clinical efficacy rate was 100%. Bacteriologically, 7 of 10 patients were eradicated, 1 was partially eradicated and 1 was persisted.
No side effect was observed, but as for abnormal laboratory findings, monocytosis in 1 case and LAP in 1 case increased transiently.
We therefore consider that BIPM is a safe and useful antibiotic in infectious diseases in surgical field.