Abstract
Plasmalogens have anti-neuroinflammatory and anti-amyloidogenic effects, thereby those might be effective for the prevention and treatment of Alzheimer’s disease. The chemical compositions of phospholipids, particularly plasmalogens, in skin and muscle tissues from post laying-eggs hen were comparatively investigated. Ethanolamine plasmalogen (PlsEtn) accounted for 21% of the skin PL, and choline plasmalogen (PlsCho) made up 6%. PlsCho was 1.8-fold more abundant than PlsEtn in the breast muscle, despite the fact that the amounts of PlsCho and PlsEtn were equal in the leg muscle. As the fatty acids composition of plasmalogens, the skin plasmalogens were found to contain more n-6 series (20 : 4 and 22 : 4), while the muscle plasmalogens were rich in 18 : 1. When the ethanol extracts of skin (high PlsEtn type) and breast muscle (high PlsCho type) were treated with phospholipase A1 followed by precipitation and partition with hexane, acetone, and water, showed a higher purity of plasmalogens. There were few changes of the phospholipid composition by the difference in chicken species and feeding environment. These findings suggest that the hens are stable and promising source of supply for plasmalogens.
