抄録
The author injected the aqueous solutions of potassium tartarate of various concentrations, each 0.5 cc per Kg, in rabbits and observed their effect on the blood pressure and pulse. On the intravenous injection of 15.7 % solution, the maximal blood pressure showed an average decrease of 23 mm Hg (18.9 %) and the minimal blood pressure showed an average decrease of 15 mm Hg (18.6 %) immediately and they returned to normal within 15 minutes after the injection. The pulse curve amplitude decreased on the average 2.1 mm (24.7 %) immediately after the injection and then recovered gradually. The pulse rate showed no definite change. On the intravenous injection of 11.7 % solution, the changes in the blood pressure were similar to those of the case above described but to a slighter degree than that. The pulse curve amplitude decreased to some extent and the pulse rate was almost unchanged. The intravenous injection of 5.9 % solution caused no remarkable change in the blood pressure and the pulse curve amplitude, and only in the pulse rate some increase was caused immediately. On the subcutaneous injection of 15.7 % solution, the maximal and minimal blood pressure decreased gradually to reach the maximal decrease in 5〜10 minutes after the injection and then recovering slowly returned to normal in 1O〜3O minutes after the injection. The average of the maximal decrease was 8 mm Hg (6.7 %) in the maximal blood pressure and 5 mm Hg (6.7%) in the minimal blood pressure. The pulse curve amplitude and the pulse rate showed no definite change. Comparing the action of potassium tartarate above described with that of potassium acetate on which the author has previously reported, the following was noted: on the intravenous injection of 4/3 normal or 1 normal solution they similarly decrease the blood pressure and differ only in the extent of this action, and on the intravenous injection of 1/2 normal solution the tartarate has no effect on the blood pressure while the acetate acts in decreasing the blood pressure.
