The Experimental Study on Allergy in Hearts of Cold-blooded Animals (IV)

Abstract

Frogs were sensitized with the same antigen shown in report I. After a period of 2∼3 weeks, the isolated frog's heart, which was fixed after Straub's method, was affected with (1 : 100) solution of labbit myocardial phosphatid and after then perfused with the mixture of rabbit myocardial phosphatid and fresh oxen sera. Amplitude of heart contraction was increased by the test solution in report II, but not increased in this experiment. Therefore, sensitized frog's heart was desensitized with phosphatid.