Abstract
Pathophysiology of acute obstruction of the superior vena cava was studied experimentally. Ligation or temporary obstruction of the superior vena cava did not threaten the life of the experimental animals. However, the cerebral blood flow reduction was remarkable especially in dogs with circulator, y disturbances. Cerebrospinal fluid drainage was proved to be effective in the case with S. V. C. obstruction to increase the cerebral venous ouflow, and this method was applied clinically with satisfactory results. Possible mechanism of this method was discussed.