1965 年 29 巻 3 号 p. 243-250
Anabolic steroids were given to nine patients placed upon long-term anticoagulant therapy to reduce raised serum lipid levels. The requirements of anticoagulants were reduced when patients receiving these drugs were administered anabolic steroids, and increased following withdrawal of them. Two of these patients developed haemorrhage following combined use of these drugs. Without anticoagulants, the administration of anabolic steroid alone did not influence prothrombin time and thromboplastin generation, remarkably. Careful control of anticoagulant dosage by Quick's one stage method and thrombotest may be required in the patients treated with anticoagulants and anabolic steroids in conjunction.
