Abstract
The hemodynamic correlation of internal carotid artery and vertebral artery before and after intravenous papaverine administration were investigated by using ultrasonic Doppler technique. (1) The blood flow pattern in vertebral artery is prone to be more discontinuous than that in internal carotid artery in the aged independent of blood pressure or cerebral vascular disease. The result suggests that the cerebral vascular resistance in the territory of vertebral artery is more increased than that in internal carotid artery in the aged. As to the mechanism of increased vascular resistance, the atherosclerosis in the territory of vertebral artery is important. (2) The vasodilation in patient with cerebral vascular disease is prone to be more less than that in subject without the disease. The result suggests that the patient with cerebral vascular disease has more tendency to fall into cerebral vascular insufficiency, since the cerebral blood vessel is already near by maximal dilatation, i.e., failure of homeostatic regulation of cerebral circulation.
