Abstract
Atrial fibrillation was initiated in a large possibility by either vagal stimulation or epinephrine injection during vagal stimulation after infusions of 2 per cent sodium lactate, 2 per cent sodium bicarbonate and 1/10N sodium-2-phosphate in closed chest dogs. The incidence of atrial fibrillation produced from 40 to 120 minutes after infusion was more frequently than that of an immediate termination of the infusion. After infusions of these solutions, serum sodium and potassium concentration increased, but serum calcium concentration decreased. Occurrence of atrial fibrillation was observed in a few cases after infusions of 1.4 per cent and 0.9 per cent sodium chloride, and was not observed after infusion of 1/10N sodium-1-phosphate at all. After infusions of these solutions, the concentration of electrolytes in serum as mentioned above did not change.
