Abstract
Various destruction in the tubero-mamillary region in hypothalamus induced hypertension and hypotension, on which etiological hormonal and neural factors were investigated pathologically, chemically and electrophysiologically, and the chronic effects of the lesions on blood pressure were compared with the acute effects of hypothalamic stimulation and destruction. The results provided the evidences that these hyper- and hypotensions were both classified into two main categories; adrenogenic and nonadrenogenic (perhaps neurogenic and partly thyroidgenic), and hypothalamic contribution to blood pressure regulation through nervous and endocrine systems was discussed in relation to the detailed localization of hypo-thalamic lesions.
